Influência do HPV na saúde oral e a perspetiva da Medicina Dentária: estado da arte

A prevalência de HPV no cancro da orofaringe está a aumentar, contudo, cancros HPV positivos tm bom prognóstico, respondem bem à terapêutica e normalmente aparecem em zonas como a base da língua, amígdalas e palato mole. É importante conhecer este vírus e quais as lesões benignas, pré-malignas e malignas que este pode induzir. Este vírus possui subtipos de alto ou de baixo risco e estão associados a lesões benignas ou malignas, sendo que o HPV 16 é o de maior perigo e as suas oncoproteínas uma das responsáveis pela transformação maligna das células do hospedeiro. Um maior conhecimento destas lesões e a sua distinção irá permitir um diagnóstico precoce, melhorando o prognóstico, assim como a educação para a saúde oral e promoção do auto exame devem ser prática corrente na consulta de medicina dentária. Das 60 referências pesquisadas, incluíndo livros, artigos e revistas, os critérios de inclusão utilizados na seleção dos artigos foram: publicações compreendidas entre o ano 2010 a 2017, artigos escritos em português e inglês e, de acordo com a pertinência e enquadramento da informação recolhida, foram efectivamente utilizados 42 referências nesta dissertação.The prevalence of HPV in oropharyngeal cancer is increasing, however, HPV positive cancer has a good prognosis, respond well to therapy, and usually appear in areas such as the base of the tongue, tonsils, and soft palate. It is important to know this virus and what benign, pre-malignant and malignant lesions it can induce. This virus has high or low risk subtypes and is associated with benign or malignant lesions, with HPV 16 being the most dangerous and its oncoproteins one off the responsible for malignant transformation of host cells. Further knowledge of these lesions and their distinction will allow an early diagnosis, improving prognosis, as well as oral health education and self-examination promotion should be current practice in the dental clinic. From the 60 references surveyed, including books, articles and journals, the inclusion criteria used in the selection of articles were: publications between 2010 and 2017 e articles written in Portuguese and English. According to consultation and classification of the information collected, 42 references were actually used in this dissertation

Applying the User-Centered Design approach for Prototyping the Interfaces of an Intelligent Emergency Management System

In today’s disaster management context, decision-making and information management is a crucial aspect, given the complexity of the tasks the decision-maker has, as well as the sheer influx of information coming in at any given time. As such there is a need to develop a system that can aid both the decision makers in the command post but can also collect the information gathered by the responders on the field. This system should also aid the decision maker by providing counselling according a set of rules, giving the system an intelligent aspect. Thusly THEMIS is born, an intelligent system to support decision making in crisis scenarios. As any given system must have an interface, the usability and user experience are a concern, but given the nature of crisis scenarios, this aspect of user interfaces becomes much more critical. It is in this context that this dissertation’s goal becomes clear: design and test the interface prototype of an emergency management intelligent system, following the User-Centered Design framework. With this goal in mind, the steps of the framework were followed, by beginning to understand the user, the context of use, resulting in understanding the user’s needs. From here, the system requirements emerged, and paper prototyping began. After validation with experts and possible users, the interfaces were prototyped digitally for both the desktop and mobile system applications. This was followed by usability tests, using the Cognitive Walkthrough method, the System Usability Score and the User Experience Questionnaire. In order to complement the testing phase, eye tracking data was gathered during the desktop version’s usability tests, which gave further insight about user behaviour. As such, it was concluded that prototypes scored highly both for usability and user experience, and there was an overall improvement on the various versions of both the desktop and mobile apps. The tests with eye tracking also allowed to identify a few issues that otherwise couldn’t be detected, namely key items the users were missing on the interfaces

Quantificação da pegada de carbono da empresa Vestas Portugal

Tese de mestrado integrado. Engenharia do Ambiente. Ramo de Gestão. Faculdade de Engenharia. Universidade do Porto. 201

Doenças autoimunes e manifestações na cavidade oral

As doenças autoimunes são consideradas como doenças inflamatórias crónicas sendo usualmente associadas a lesões orais dolorosas. As manifestações orais podem ser consideradas como os primeiros sinais/sintomas de diversas patologias autoimunes como a Artrite Reumatóide, o Pênfigo, entre outras. Em termos imunopatológicos podemos classificar as lesões orais, maioritariamente, associadas a doenças autoimunes reumáticas, ulcerosas e bolhosas. É de vital importância uma intervenção precoce, muitas vezes associada a um diagnóstico preciso, com uma boa comunicação entre uma equipa médica multidisciplinar incluindo o médico dentista. Estas patologias necessitam, para além do diagnóstico correto, a familiarização com as terapêuticas existentes de forma a definir um melhor plano de tratamento para o individuo, a reduzir a morbilidade destas patologias e melhorar assim a qualidade de vida do paciente.Autoimmune diseases are considered chronic inflammatory diseases being usually associated with painful oral lesions . Oral manifestations may be considered as early signs/symptoms of several autoimmune diseases like Rheumatoid Arthritis (RA), Pemphigus, between others. As immunopathological conditions we can classify the oral lesions, as mainly associated, with Rheumatic, ulcerous and bullous autoimmune diseases. It's vitally important an early intervention, in several cases associated with a precise diagnostic, and a good communication between a multidisciplinary medical team including the medical dentist. These pathologies need, beyond the correct diagnostic a familiarization with the existing therapies, to define the better treatment plan for the individual thereby reducing the morbidity and improving the quality life of the patient

The Behavioral Regulation in Exercise Questionnaire (BREQ-3) Portuguese-Version: Evidence of Reliability, Validity and Invariance Across Gender

This study has as prime objective to analyze the psychometric properties of the Behavioral Regulation Exercise Questionnaire (BREQ-3) in a sample of Portuguese exercisers and invariance across gender. Two independent samples (448 calibration; 374 validation), aged between 16 and 78 years (M = 40.29; SD = 16.24), of both gender, (495 female; 327 male) were enrolled in this study. The results show that the original model (six factors; 24 items) did not fit to the data in a satisfactory way (χ 2 = 977.49; df = 237; B-S p < 0.001; SRMR = 0.07; NNFI = 0.80; CFI = 0.83; RMSEA = 0.08; 90% CI = 0.08–0.09). After removing six items (one for each factor), the model (six factors; 18 items) adjustment improved in a satisfactory way in both samples: calibration (χ 2 = 331.86; df = 120; B-S p < 0.001; SRMR = 0.06; NNFI = 0.91; CFI = 0.93; RMSEA = 0.06; 90% CI 0.06–0.07) and validation (χ 2 = 254.08; df = 120; B-S p < 0.001; SRMR = 0.04; NNFI = 0.93; CFI = 0.95; RMSEA = 0.06; 90% CI = 0.05–0.06). Results also showed model invariance across gender (1CFI ≤ 0.01). The Portuguese version of BREQ-3 (six factors; 18 items) is a valid and reliable measurement instrument to measure behavior regulation underlying self-determination theory in the exercise domain. However, the evidence also indicated that additional studies are needed to address the fragilities of the original model (six factors; 24 items).info:eu-repo/semantics/publishedVersio

Implementation of a Private Cloud

The exponential growth of hardware requirements coupled with online services development costs have brought the need to create dynamic and resilient systems with networks able to handle high-density traffic. One of the emerging paradigms to achieve this is called Cloud Computing it proposes the creation of an elastic and modular computing architecture that allows dynamic allocation of hardware and network resources in order to meet the needs of applications. The creation of a Private Cloud based on the OpenStack platform implements this idea. This solution decentralizes the institution resources making it possible to aggregate resources that are physically spread across several areas of the globe and allows an optimization of computing and network resources. With this in mind, in this thesis a private cloud system was implemented that is capable of elastically leasing and releasing computing resources, allows the creation of public and private networks that connect computation instances and the launch of virtual machines that instantiate servers and services, and also isolate projects within the same system. The system expansion should start with the addition of extra nodes and the modernization of the existing ones, this expansion will also lead to the emergence of network problems which can be surpassed with the integration of Software Defined Network controllers

Business plan for an innovative tutoring and study center

This thesis is the elaboration of a business plan for developing a totally innovative center in Portugal. It is innovative because there are still no places like this in our country. The project consists in a tutoring center which encloses a space exclusively for studying and also a cafeteria service, meaning that students can come to the center to study, make their homework and individual or group Works, once they have space and conditions to do so: tables, chairs, internet WIFI and all the commodities needed. But they can also opt for having tutoring sessions on some curricular unities, in which they might have difficulties. All this is associated to a cafeteria service which allows for students to eat and drink something without having to leave the center. There will also be a high technological printer, which can print any type of work in high quality and that students can use to print the work they make at the center. However, for the creation of a center like the one described to be possible, it is necessary to make diverse studies. Firstly, a literature review on strategic management and business plans has been made. Next, has proceeded a market analysis. Only after making a market analysis it was possible to create a marketing plan. Finished the marketing plan, it was elaborated a management plan. To conclude, it is necessary to make the entire financial analysis in order to have a perception of the business’s viability.Esta tese é a elaboração de um plano de negócios para a criação de um centro totalmente inovador em Portugal. É inovador porque no nosso país ainda não existe nada deste género. O projeto consiste num centro de explicações que engloba um espaço de estudo e um serviço de cafetaria, o que significa que estudantes podem ir ao centro apenas para estudar, fazer trabalhos de casa e trabalhos individuais ou de grupo, uma vez que têm espaço e condições para tal: mesas, cadeiras, acesso à internet e todas as comodidades pretendidas. Mas podem também optar por ter explicações de alguma unidade curricular em que estejam a sentir dificuldades. Tudo isto está associado a um serviço de cafetaria que permite aos estudantes comerem e beberem qualquer coisa sem terem de sair do centro. Haverá também uma impressora de tecnologia avançada que permite a impressão de qualquer tipo de trabalho com elevada qualidade e que os estudantes podem utilizar para imprimir trabalhos que tenham feito no centro. Contudo para que seja possível a criação de um centro como o descrito, é necessário realizar diversos estudos. Primeiramente realizou-se uma revisão literária sobre gestão estratégica e planos de negócios. De seguida procedeu-se a uma análise de mercado. Apenas depois de fazer uma análise de mercado foi possível criar um plano de marketing. Terminado o plano de marketing, elaborou-se um plano de gestão. Para concluir, é necessário fazer toda a análise financeira a fim de percecionar a viabilidade do negócio

Case study: Lisbon: A dream destination?

O turismo é um fenómeno marcante do século XXI, assumindo importância nas mais variadas esferas que compõem a vida em comunidade, constituindo uma égide económica, política, cultural e social difícil de encontrar em outros sectores da sociedade. Este caso pedagógico insere-se nessa problemática, partindo de um conjunto de tendências de turismo internacionais para a focalização num destino específico, a capital de Portugal, Lisboa. Tendo em vista uma discussão globalizante e integrante dos diversos temas que confluem para a gestão estratégica e promoção de um destino turístico enquanto marca, serão apresentados um conjunto de dados que servirão de base para um estudo aprofundado do mercado turístico lisboeta, avaliando primordialmente as dimensões de posicionamento e imagem percebida do destino, partindo ainda de determinadas características que definem o perfil do seu público-alvo. Lisboa enquadra-se num cenário competitivo forte, no qual procura distinguir-se dos principais destinos Europeus através de uma estratégia holística que tem por base um alinhamento entre os diversos produtos turísticos da cidade e região e que contribuem para o seu posicionamento genérico enquanto destino turístico. Para facilitar o entendimento do caso será efectuada uma abordagem ao tema de marketing estratégico de destinos turísticos, no que toca sobretudo aos conceitos de marca, imagem e comportamentos do consumidor em turismo. O cariz pedagógico é atribuído pela actualidade e recente importância de Lisboa no panorama internacional do turismo espelhando uma perspectiva futura optimista e contribuindo decisivamente para a alavancagem da sociedade portuguesa, não só a nível económico como também social e espiritual.Tourism is a noticeable phenomenon of the XXI century, assuming critical importance in the several spheres that compose life in community, constituting an economic, political, cultural and social aegis hard to find in other areas of society. This case study is edged under this problematic, starting from a set of international tourism trends to focus on a specific destination, the capital of Portugal, Lisbon. Key facts will be presented, seeking for a globalizing and integrating discussion around the diverse themes that comprise the strategic management and brand promotion of a tourism destination, involving a deep study of the Lisbon tourism market, primarily evaluating its perceived image and positioning dimensions and relating to its specific target markets profile characteristics. Lisbon is framed on a strong competitive scenario, striving for a differentiation relatively to the main European destinations through holistic strategies based on a principle of alignment between the several tourism products of the city and region that contribute for its overall positioning as a destination. A literature review will be presented, in order to contribute for a generic comprehension of the case study, highlighting key concepts of destination strategic marketing, such as branding, image and consumer behavior in tourism. The educational character is attributed by the hot topic and recent importance of Lisbon in the international tourism panorama reflecting an optimistic future perspective, aiming at decisively contributing to the leverage of the Portuguese society, not only at an economic level, but also considering a social and spiritual dimension.http://hdl.handle.net/10071/518